Armodafinil tablets are prescription medication for adults with narcolepsy or obstructive sleep apnea, used alongside other treatments to boost wakefulness.
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What is Armodafinil?
The generic medicine Armodafinil is a stimulant that improves excessive daytime sleepiness. It is the R-enantiomer of the racemic Modafinil and was approved by the FDA in the year 2007.
Armodafinil Facts
| Drug class | Central nervous system stimulant |
|---|---|
| Armodafinil manufacturer | Cephalon Inc. |
| Armodafinil legality | USA- Schedule IV (Prescription only) |
| Inactive ingredients | Microcrystalline cellulose, croscarmellose sodium, povidone, pregelatinized starch, lactose monohydrate, and magnesium stearate. |
Mechanism Of Action
Armodafinil works by increasing the production of the neurotransmitter dopamine in the brain by preventing its reuptake and promotes the levels of other neurotransmitters such as orexin, histamine, glutamate, and norepinephrine all of which contribute to its wakefulness property.
Armodafinil also restricts the action of Gamma-Aminobutyric Acid that triggers sleepiness when available in high amounts.
What Are The Uses And Benefits Of Armodafinil?
Armodafinil pills are primarily used and approved by the FDA to treat excessive sleepiness associated with the following conditions –
Narcolepsy- Shift Work Sleep Disorder
- Obstructive Sleep Apnea:
Narcolepsy is a sleep disorder characterized by excessive attacks of daytime sleepiness and disrupts the normal sleep-wake cycle. About 1 in 2,000 people in the United States is affected by this condition.
Shift Work Sleep Disorder is a chronic condition that arises when the natural sleep cycle of a person is disrupted persistently due to work shifts.
Obstructive Sleep Apnea is a breathing disorder related to sleep where the throat muscles relax and block the airway, resulting in abnormal breathing during sleep.
Armodafinil is commonly used off-label to treat
Chronic fatigue syndrome- Major depressive disorder
- Attention deficit hyperactivity disorder (ADHD)
- Bipolar disorder
- Jet lag
- Schizophrenia
Chronic fatigue syndrome, also termed myalgic encephalomyelitis, is a disease that is characterized by severe fatigue, sleep problems, autonomic dysfunction, and cognitive dysfunction, which impairs a person's ability to do everyday tasks.
Major depressive disorder or clinical depression is a mental disorder characterized by low mood, loss of interest, and low self-esteem. It is ranked as the third cause of burden of disease worldwide by WHO in the year 2008.
Attention deficit hyperactivity disorder includes a combination of issues such as difficulty in paying attention, hyperactivity, and impulsive behavior. It is a long-term condition that affects millions of children and often continues till adulthood.
Bipolar disorder is a serious mental illness that is characterized by mood shifts ranging from extreme highs (mania) to extreme lows (depression). This mental illness affects 2.8% of people in the United States, and the World Health Organization considers this condition as the sixth leading cause of disability worldwide.
Jet lag is a combination of fatigue and other symptoms caused by traveling across different time zones. This condition is also known as 'time zone change syndrome.
Schizophrenia is a mental illness that impacts less than one percent of the U.S. population and is characterized by some combination of hallucinations, delusions, and disoriented behavior and thinking that impairs a person's everyday life.
In various studies, Armodafinil has been found beneficial in treating all the conditions mentioned above, but before taking this effective nootropic for off-label purposes, it is important to talk to a healthcare professional.
Armodafinil Benefits
- Armodafinil has a longer half-life. Therefore, this nootropic provides prolonged effectiveness.
- It has a quick onset of action that is 30 minutes.
- Armodafinil is well tolerated by most people.
- Armodafinil has a longer half-life. Therefore, this nootropic provides prolonged effectiveness.
- It has a low chance of dependence.
- A lower dose of this drug provides similar efficacy compared to a higher Dose of other medicines of the same class.
What Are The Different Brands Of Armodafinil?
Armodafinil is available under various brand names, such as Artvigil and Waklert.
Artvigil Vs. Waklert
Both Artvigil and Waklert are composed of Armodafinil. Therefore, they share a lot of similarities as well as differences.
| Artvigil | Waklert | |
|---|---|---|
| Active ingredient | Armodafinil | Armodafinil |
| Price | $1 per pill | $1.25 per pill |
| Effectiveness | Good, 12 hours | Excellent, 14 to 16 hours |
| Standard dosage | 150 mg | 150 mg |
| Is this a controlled substance? | Yes | Yes |
| What is the typical length of treatment? | Long-term treatment | Long-term treatment |
| Manufacturer | HAB Pharmaceuticals. Ltd | Sun Pharmaceutical. Ltd |
The Bottom Line – Furthermore, Waklert is more costly in comparison to Artvigil, but Waklert is much superior when it comes to effectiveness.
Dosage And Administration Guidelines Of Armodafinil
Armodafinil is exclusively available in the doses strengths of –
- Armodafinil 50 mg
- Armodafinil 150 mg
- Armodafinil 200 mg
- Armodafinil 250 mg
The recommended standard dose of Armodafinil is 150 mg. For Narcolepsy and Obstructive Sleep Apnea, the recommended dose of the nootropic is 150-250 mg, taken in the morning.
For Shift Work Sleep Disorder, the recommended dose of this stimulant is 150 mg, which should be consumed 1 hour prior to work.
Administration Guidelines
- Take the smart drug as prescribed.
- Breaking the medicine is not advisable.
- Do not chew or crush the medicine.
- Take the medicine orally with water.
- Follow all the instructions given by your healthcare professional while taking Armodafinil.
Potential Armodafinil Side Effects
Most of the side effects of Armodafinil are mild and get better over time as the body gets used to the medicine.
7 Common side effects
- Headache
- Nausea
- Dizziness
- Anxiety
- Diarrhea
- Dry mouth
- Insomnia
Headache is a painful sensation in the head or face area.
Nausea is an uneasiness in the stomach that is accompanied by an urge to vomit, weakness, increased saliva, and sweating.
Dizziness is a feeling of being woozy, off-balance, and lightheadedness.
Anxiety is an emotion that is characterized by tension, uneasiness, worry, or fear ranging from mild to severe.
Diarrhea is the passage of watery or loose stools, usually occurring more often than usual.
Dry mouth occurs when there is a lack of saliva production by the salivary glands.
Insomnia is a common sleep disorder that makes it hard to fall asleep and stay asleep.
4 Other side effects
- Depression
- Fatigue
- Palpitation
- Upset stomach or ingestion
Depression is a condition that is characterized by extremely low mood, severely impacting the everyday life of an individual
Fatigue is described as a feeling of overall tiredness and lack of energy.
Palpitation is defined as the rapid, irregular beating of the heart that is noticeable.
Indigestion is a condition that is characterized by pain or burning feeling in the upper abdomen of the stomach.
Talk to your doctor immediately if you experience any of the following after taking Armodafinil capsules –
- Rare severe skin reactions.
- Allergic reactions
- Chest pain, irregular heartbeat
- Worsening of mania, depression, or suicidal tendencies.
Precautions And Warnings Things To Keep In Mind
- Proper Armodafinil dosage guidelines must be followed to avoid abuse and dependency.
- Do not drive or operate other machinery until and unless you know how this medicine affects you.
- Kidney, liver, and heart patients should use Armodafinil cautiously.
- Before taking Armodafinil, tell your doctor if you are allergic to the ingredients of the Nootropic.
- Do not consume alcohol with the Nootropic.
- Individuals below the age of 18 should refrain from taking Armodafinil.
- Do not stop taking the medicine suddenly without consulting your doctor.
- Pregnant and breastfeeding women should not take Armodafinil without a doctor’s consultation.
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